(R)-3-Amino-4-(2,4,5-Trifluorophenyl)butyric Acid Hydrochloride - Names and Identifiers
Name | (R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid-HCl
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Synonyms | Sitagliptin-butanoic acid (R)-3-Amino-4-(2,4,5-trifluorophenyl)butyric acid Benzenebutanoic acid, β-aMino-2,4,5-trifluoro-, (βR)- Benzenebutanoic acid, b-aMino-2,4,5-trifluoro-, (bR)- (R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid-HCl (R)-3-Amino-4-(2,4,5-Trifluorophenyl)butyric Acid Hydrochloride Benzenebutanoic acid, .beta.-aMino-2,4,5-trifluoro-, (.beta.R)- tert-butyl (R)-1-(Methoxycarbonyl)-3-(2,4,5-trifluorophenyl)propan-2-ylcarbaMate Tert-butyl(R)-1-(methoxycarbonyl)-3-(2,4,5-trifluorophenyl)propan-2-ylcarbamatetert-butyl(R)-1-(methoxycarbonyl)-3-47(2,4,5-trifluorophenyl)propan-2-ylcarbamate
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EINECS | 1308068-626-2 |
(R)-3-Amino-4-(2,4,5-Trifluorophenyl)butyric Acid Hydrochloride - Physico-chemical Properties
Molecular Formula | C10H10F3NO2
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Molar Mass | 233.19 |
Density | 1.399 |
Melting Point | 217-219 °C(Solv: water (7732-18-5); acetone (67-64-1)) |
Boling Point | 326.6±42.0 °C(Predicted) |
pKa | 3.66±0.10(Predicted) |
Storage Condition | 2-8°C(protect from light) |
(R)-3-Amino-4-(2,4,5-Trifluorophenyl)butyric Acid Hydrochloride - Introduction
(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid-HCl is a pharmaceutical compound which is in the form of a salt of (R)-3-amino -4-(2,4, 5-trifluorophenyl) butanoic acid and hydrochloric acid. This compound has the formula C10H11F3NO2. HCl and a molecular weight of 297.66.
(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid-HCl is often used as an anti-epileptic drug to control seizures or reduce their frequency and intensity.
In preparation, (R)-3-amino -4-(2,4, 5-trifluorophenyl) butyric acid can be first synthesized, and then reacted with hydrochloric acid to obtain hydrochloride.
Regarding safety information, due to the application of compounds in the field of medicine, the relevant toxicology and safety evaluation have been mastered. When using, it is necessary to use the medicine accurately according to the doctor's advice, and the dosage cannot be adjusted without authorization. Possible side effects include drowsiness, dizziness, nausea, vomiting, etc. Serious side effects are rare, but the patient's response and physiological indicators still need to be closely monitored. During use, the precautions in the drug product instructions should be followed, and the compound should be stored and handled in the correct way.
Last Update:2024-04-09 21:21:28